insurance coverage for glp-1 medications Navigating Changes to Medication Researchers study barriers to GLP-1

The manufacturer (EMD Serono) voluntarily discontinued Geref in 2008 for commercial reasons, not because of safety issues

Tesamorelin is a synthetic 44-amino acid analog peptide

Back Trapp, S, Brierley, DI (29 July 2021) 'Brain GLP-1 and the regulation of food intake: GLP-1 action in the brain and its implications for GLP-1 receptor agonists in obesity treatment' British Journal of Pharmacology

Over 29 days of treatment, the peptide inhibited pulmonary artery muscularization (the thickening and stiffening of pulmonary arteries that drives this condition), prevented right heart hypertrophy (the enlargement of the right ventricle that occurs when it has to pump against increased resistance), and significantly decreased mortality