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Nevertheless, the pooled analysis of 16 trials suggested improvements in the summary measure of patients' global functioning (assessed with the Clinical Global Impressions [CGI-I] scale) after 12 and 24 weeks of (but not after 52 weeks) of ALCAR treatment (1-3 g/day) and in cognitive performance (assessed with the Mini-Mental State Examination [MMSE] scale) after 24 weeks (but not at 12 or 52 weeks) (104)

Each capsule delivers 2 Billion TFU of Akkermansia muciniphila, a strain renowned for its role in enhancing gut barrier integrity, modulating GLP-1 secretion, and promoting healthy glucose metabolism

Therefore, both prophylactic and therapeutic strategies of bilirubin administration are being considered

doi: 10.1016/j.physbeh.2007.04.006, 93 MarkeyC