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The inclusion of multiple peptides allows for broader analysis of interconnected systems within controlled laboratory settings

The authors identified future areas of investigation including male models, long-term treatment effects, and combination with other NAD+ precursors such as NMN

Nature PubMed Preclinical literature and narrative reviews describe pleiotropic actions including angiogenesis modulation (promotion in healing contexts and proposed inhibition in rodent corneal neovascularization models) and purported cytoprotective effects across diverse injury paradigms, but these remain unconfirmed in controlled human experiments

Instead, it is a powerful biological tool that works best when dosage, timing, delivery, and combination therapy are carefully tailored to individual physiology and goals