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Description

HO-1 is a stress-induced, anti-inflammatory, immune-modulatory, and cyto-protective enzyme that degrades heme into carbon monoxide, free iron, and biliverdin 47 , consequently, the virus-induced HMRD could compromise host innate and adaptive immune responses

Glutathione synthesis

ZEN 2.3 (blue edition) software was used for acquisition of images from confocal microscope

Nanoparticles were diluted in phenol red-free DMEM/HAMs F-12 medium (Gibco, Life Technologies, Carlsbad, CA, USA) supplemented with 5% FBS at a final concentration of 100 g/ml and added to the donor compartment (0.2 ml)