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There are great variations in nuclear GSH concentration and its regulation mechanisms during the cell cycle since cells starting the proliferation phase have high levels of nuclear GSH, while resting cells have similar or lower GSH levels in the nucleus than in the cytoplasm (68, 72, 73)

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The cases with an H -score less than the cut-off value were regarded as low GSTM3 expression, while the others were high GSTM3 expression

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