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Dosing After Reconstitution With a 10 mg vial reconstituted in 2 mL BAC water (5 mg/mL concentration): For the 8 mg and 12 mg doses, a higher concentration is more practical
Those in the semaglutide 1.0 mg arm received 0.25 mg for 4 weeks, followed by 0.5 mg for 4 weeks and 1.0 mg for 5 weeks
This concentration shines during the titration phase when you might want to adjust in smaller increments than the standard 2.5 mg jumps
Clinical trials commonly start with 1 mg weekly and gradually increase the dose to higher levels such as 4 mg, 8 mg, or even 12 mg depending on the study protocol
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