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Because mitochondria lack GSH biosynthetic machinery 5 and GSH is negatively charged under physiological conditions 10 , it must enter mitochondria through a dedicated transport process
Our work underscores the value of studying family-wide genetic interactions across different metabolic environments
Specifically, SOD1 catalyzes the conversion of O 2 - into H 2 O 2 , thereby reducing the levels of ROS and mitigating oxidative stress [37]
Yaghubi E, Daneshpazhooh M, DJalali M, Mohammadi H, Sepandar F, Fakhri Z, Ghaedi E, Keshavarz SA, Balighi K, Mahmoudi H, Zarei M, Javanbakht MH (2019) Effects of l -carnitine supplementation on cardiovascular and bone turnover markers in patients with pemphigus vulgaris under corticosteroids treatment: a randomized, doubleblind, controlled trial
