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Patients were treated with diet and exercise alone (19%), a single oral antidiabetic agent (47%), or combination therapy of oral antidiabetic agents (35%)
Particularly, the reduction of GLP-1 release over time has been an observed feature of T2DM development, as GLP-1 reduces glucagon secretion and hepatic gluconeogenesis while promoting insulin secretion, thereby effectively minimizing hyperglycemia [106]
It is crucial to emphasise that probiotics are not a treatment for the underlying conditions requiring GLP-1 therapy , nor are they proven to prevent or eliminate GLP-1-related side effects
But still, it's fascinating to see how scientists can manipulate something so deadly, and turn it into something else entirely.
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