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In addition, malignant serous ovarian tissue samples showed significantly higher reactive carbonyl contents compared with non-diseased controls (p = 0.009), while GPX3 levels were markedly decreased in serous cystadenoma and malignant tissue samples, as well as in non-diseased controls, compared with borderline tumors

doi: 10.1056/NEJMOA1503734 266 OlsenSFsterdalMLSalvigJDMortensenLMRytterDSecherNJet al

Teijeira A, Garasa S, Ochoa MC, Villalba M, Olivera I, Cirella A, et al

Glutathione depletion is linked with Th2 polarization in mice with a retrovirus-induced immunodeficiency syndrome, murine AIDS: role of proglutathione molecules as immunotherapeutics