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h-l , C4-2 cells were subjected to mouse xenograft assays, When the tumor reached 50 mm3, the mice were assigned randomly into different treatment groups treat with RSL3 (100 mg/kg) combined with or without GSK3326595 (40 mg/kg), Tumor sizes were monitored ( h ) until the endpoint at day 30, and dissected tumors were weighed ( i-j )