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Acknowledgments We thank Kristin Marie Bivens (Institute of Social and Preventive Medicine ISPM) for her editorial assistance

Semaglutide primarily affects appetite regulation and glucose metabolism through GLP-1 signaling, while MOTS-C influences mitochondrial metabolism and cellular energy regulation

If youre here because of a missed GLP-1 dose, whether that be semaglutide or tirzepatide, you need to know what your options are and how to take the next step