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In a 2003 in vitro experiment by Khavinson and colleagues, addition of micromolar concentrations of the peptide to cultured human somatic fibroblasts produced a measurable increase in telomerase reverse transcriptase activity and a corresponding extension of telomere length across 1020 passages, with cell cultures continuing to divide beyond the Hayflick limit observed in untreated controls
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When mitochondria, the organelles in cells that power our bodies, process oxygen, between 1% and 2% gets left behind as free radicals known as reactive oxygen species
A mitochondrial respiration medium (MiR05) containing sucrose 110 mM, HEPES 20 mM, taurine 20 mM, K-lactobionate 60 mM, MgCl 2 3 mM, KH 2 PO 4 10 mM, EGTA 0.5 mM, BSA 1 g/l, pH 7.1 was used for all experiments
