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I often get warmth and discomfort afterwards

B12, dare we say it, has become almost fashionable

Thymosin Beta-4 Improves Endothelial Function and Reparative Potency of Diabetic Endothelial Cells Differentiated From Patient Induced Pluripotent Stem Cells, Su L, Kong X, Loo S, Gao Y, Liu B, Su X, Dalan R, Ma J, Ye L, Stem Cell Research & Therapy, 2022 Jan 10;13(1):13

Healthline notes that another side effect of too much vitamin B12 is the development of a rare and slow-growing blood cancer known as "polycythemia vera" (PV)