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Phase 2 data published in 2023 reported mean body-weight reductions of up to 24.2% at 48 weeks on the highest dose tier (Jastreboff et al., NEJM 2023)
Food Workaround A weekly injection creates a new challenge because once the drug is in your system, you cannot reverse it
Common Factors That May Slow Progress High-calorie or ultra-processed diets Irregular medication use Lack of physical activity Poor sleep patterns Addressing these can improve outcomes over time
The study, which was published in the journal Endocrine Connections , was called Glucagon-like peptide 1 receptor agonists and thyroid cancer: is it the time to be concerned? The studys authors suggested that more research will be needed to see if GLP-1 drugs, like Zepbound, may have carcinogenic-like effects in the human body
