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View Study [4]"Inhibition of activin-like kinase 4/5 attenuates cancer cachexia associated muscle wasting" Levolger S, Wiemer EAC, et al., 2019 Finding: LR3 IGF-I treatment effectively limited muscle mass loss in a cancer cachexia model, demonstrating its potent anti-catabolic effects and ability to preserve muscle tissue under conditions that normally cause severe muscle wasting
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was supported by Takeda Science Foundation 2019 Medical Research Grant and Japan Science and Technology Agency PRESTO (18069571)
The identified glutathione-related pathways provide potential therapeutic targets for alleviating oxidative stress-induced hippocampal injury in SAE, offering new insights for the clinical management of SAE-related neurological damage
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