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Where you fall on that spectrum should inform your decision
Some of these include nausea and pain at injection site
In contrast, exenatide immediate-release and lixisenatide should be administered before meals (within 60 minutes before the main meals of the day)
Why Weight Loss Plateaus on Semaglutide or Tirzepatide and What to Do About It Joshua Silva, MD Dec 16, 2025 6 min read Updated: Jan 15 Medically authored by Joshua Silva, MD | Evidence-Based Weight Loss at Potere Health MD Last clinically updated: December 2025 Many people taking semaglutide or tirzepatide notice that weight loss is faster at first and then slows or pauses over time
