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Long-term exposure of mice to nucleoside analogues disrupts mitochondrial DNA maintenance in cortical neurons
Avoid repeated contamination of the vial
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But It comes with significantly higher discontinuation rates A concerning rate of dysesthesia And potential cardiac safety issues that require further investigation The headline 28.7% weight loss is impressive but the real-world difference vs tirzepatide is only about 3% , and side effects may be more pronounced
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