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The characteristic of diabetic retinopathy is alterations to the bloodretinal barrier (BRB), which can lead to retinal neovascularization when hypoxia occurs [24]
BMO Capital Markets analyst Etzer Darout in a note to investors said that AstraZeneca believes that AZD5004 is differentiated from other GLP-1 therapies in development and on the market, particularly given its favorable tolerability. Further helping AZD5004 distinguish itself in the crowded obesity space is its reduction in glucose and body weight in patients with type 2 diabetes and its simplified manufacturing path, Darout wrote
2017 Jul 1;55(7):7-11
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