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Semaglutide and icodec were incubated on a HulaMixer TM (Thermo Fisher Scientific, Waltham, MA, USA) for 2 h at room temperature with different concentrations of immobilised HSA in phosphate buffered saline (pH 7.4) and a final concentration of 0.005% Tween 20
And FDA warning letters going back years
2.3.1 Location of Modification The acetylation modification occurs precisely at the thiol group site of the cysteine residue, not at any other position of the molecule
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