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SELENOP-independent Se transport to neuronal tissue may be attributed to selenosugars (Solovyev et al., 2013)
While IGF-1 has insulin-agonistic actions and has been used for treatment of severe insulin resistance, IGF-1 reduction with the GH antagonist pegvisomant improves glycemic control in acromegalic patients with diabetes or impaired glucose tolerance despite elevated GH (35, 36)
Research on Melanotan 1 has focused on its usefulness in treating disorders such as erythropoietic protoporphyria (EPP), a condition causing heightened sensitivity to sunlight, and vitiligo, characterised by uneven skin pigmentation
PMID: 10995836 PMCID: DOI: 10.1523/JNEUROSCI.20-18-06920.2000
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