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p = 9.07 E-19), which are known to mediate excretion of glucuronides from hepatocytes ( Abcc3 mRNA increased about 3-fold and Abcc4 about 16-fold in the livers of cirrhotic mice (Figure 6F)
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Lilly reported that patients on retatrutide lost a large average percentage of body weight, and some patients moved below the obesity range
Initially approved for diabetes, it saw remarkable weight reduction in patients, leading to its approval for obesity management
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