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Based on these results, we prioritized oral Bimiralisib and Paxalisib, and IV Gedatolisib, for evaluation of concordance between in vivo and in vitro PK profiles in patient-specific NOCS platforms to select the most suitable oral compound (Supplementary Table 13 and Table 14)
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People who have a genetic predisposition for lower GSH production have an even greater challenge maintaining sufficient GSH
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