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The grey bar represents the 30% level of functional hepatocytes below which liver failure is thought to occur [38]

527 Conclusions and perspective Primarily recognized for their role in diabetes mellitus treatment, GLP-1RAs have demonstrated significant benefits in cardiovascular health, skeletal muscle-related diseases, obesity management, and neurodegenerative conditions, among others

While GLP 1s work on appetite, digestion, and insulin, amylin analogues influence fullness and food reward in a deeper way

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