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Medication Characteristics As a GLP-1 receptor agonist, semaglutide works by enhancing glucose-dependent insulin secretion while reducing glucagon secretion

In the context of SUD, such mechanisms could plausibly reduce craving and compulsive drug-seeking, aligning with preclinical work showing attenuation of substance-related reinforcement and with emerging clinical data suggesting reduced alcohol-related outcomes among GLP-1RA users (18, 35)

This transition period is designed to help patients and providers avoid sudden disruptions in treatment, but it also means that anyone relying on compounded Semaglutide will need to make plans to switch to FDA-approved medications soon