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While heart palpitations specifically are not listed among the common adverse reactions in the FDA prescribing information for semaglutide products, increased heart rate is a documented effect, particularly with Wegovy
Visschers et al., 2012
CrossRef High-fat diet, gut dysbiosis, and oxidative stress: A synergistic triangle in metabolic dysfunction-associated steatotic liver disease pathogenesis Zi-Rui Zhang, Ling She, Yi-Rong Cao, Yuan-Wen Chen World Journal of Hepatology .2026;[Epub] CrossRef Fibulin-3 as a reliable biomarker of fibrosis in obese subjects with metabolic dysfunction-associated steatotic liver disease Allen Anthony Larao, Silvia Palmisano, Deborah Bonazza, Discipio Marina, Marica Meroni, Anna Ludovica Fracanzani, Lory S Croc, Claudio Tiribelli, Paola Dongiovanni, Natalia Rosso, Pablo Giraudi Annals of Hepatology .2026