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In laboratory models, the compound has been associated with upregulation of the nitric oxide (NO) system, modulation of vascular endothelial growth factor receptor 2 (VEGFR2), and activation of focal adhesion kinase (FAK) pathways implicated in angiogenesis, cell migration, and tissue repair

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Discontinuation typically results in weight regain, with patients recovering approximately two-thirds of lost weight within 12 months after stopping treatment