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Regarding the question of what these results tell us about dietary supplementation, this study serves as a reminder of the importance of seeking professional advice when taking supplements
In this situation, it can be challenging to demonstrate B12 deficiency even when there are typical symptoms (including neuropathy-like paraesthesia and numbness), as serum B12 concentrations may be just within, or sometimes above, the normal range due to the oral supplementation
PLoS ONE 6 , e17397
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