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Blood samples were collected from the portal vein or the gastric vein before and 15 and 30 min after the load
Im just looking for options that feel true to me at this stage, knowing things can always change down the road
According to FDA prescribing information, nausea occurs in 17-25% of patients taking Mounjaro and 24-31% with Zepbound, constipation in 10-17% (Mounjaro) and 16-24% (Zepbound), and diarrhea in 12-17% (Mounjaro) and 18-23% (Zepbound), with incidence varying by dose
The principle remains intellectually compelling and mechanistically supported, but clinical demonstration of superiority based on signaling bias alone has yet to be robustly established for most peptide targets
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