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While semaglutide is an excellent GLP-1 agonist, tirzepatides dual receptor activity appears to enhance satiety, improve insulin signaling, and reduce cravings in ways that translate into deeper weight reduction for many patients
Choose psyllium (Metamucil-type fiber) if you want stronger fiber effects and dont mind some potential bloating
The 2014 Beck Phase 2 randomised controlled trial published in the International Journal of Colorectal Disease provides the clinical-research-stage data point (PMID 25331030)
Am J Physiol Heart Circ Physiol 2008
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