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GLP-1R agonism produces: Glucose-dependent insulin secretion (insulin released only when glucose is elevated) Suppression of glucagon secretion Delayed gastric emptying (contributing to satiety) Reduced appetite via central nervous system signalling in hypothalamic nuclei Potential cardiovascular protection (observed in clinical trials of GLP-1 agonist drugs) This receptor is the foundation of the entire GLP drug class, from exenatide to semaglutide
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Since it is a water-soluble vitamin and your body uses just what it needs at that time and eliminates the excess through the bodys normal waste process, it cannot build up in your system
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