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This naturally occurring copper-binding tripeptide is synthesized to 99% purity, with every lot independently tested by Janoshik Analytical

The loading phase uses 0.25mg daily subcutaneous injection to assess individual tolerance

However, with long-acting GLP-1 RAs, the body may develop tolerance (tachyphylaxis) to this specific effect over time (Dungan & DeSantis, 2026)

Released rapidly in response to nutrient ingestion, especially carbohydrates and fats, it enhances insulin secretion from pancreatic beta cells in a glucose-dependent manner, effectively lowering postprandial blood glucose without risking hypoglycemia