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Absorption from an intramuscular dose has been measured between 55% and 97%

A COA showing 99% HPLC purity and 80% peptide content means the sample is very pure (99% of detected material is AHK-Cu), but only 80% of the sample weight is actually active peptide base (the other 20% is water, TFA salt, and other non-peptide components)

If needed for a clear medical indication (such as treating pellagra in a pregnant patient), niacinamide can be used with caution, but unnecessary high-dose B supplementation is avoided in pregnancy