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Angiotensin II can directly induce mitochondrial dysfunction, decrease oxidative fibre number and induce atrophy in mouse hindlimb skeletal muscle

Contact your GP if you experience: Persistent metallic taste lasting beyond 23 weeks despite self-management strategies Complete loss of taste (ageusia) or significant taste distortion affecting nutritional intake Taste changes accompanied by other concerning symptoms such as severe nausea or vomiting Inability to keep fluids down or signs of dehydration (excessive thirst, dry mouth, dark urine, dizziness) Oral symptoms including mouth ulcers, swelling, pain, or signs of infection Difficulty maintaining adequate food or fluid intake due to taste disturbance Symptoms suggestive of hypoglycaemia, particularly if taking Ozempic with insulin or sulphonylureas (sweating, shakiness, confusion) [1] [2] Seek same-day medical advice if you have persistent vomiting with signs of dehydration or cannot keep fluids down

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