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10.1038/nchembio.362 12 DingY.ChenX.LiuC.GeW.WangQ.HaoX.et al (2021)
307,413 In terms of apoptosis inhibition, GLP-1 activates the PI3K/Akt signaling pathway, enhances the expression of the anti-apoptotic protein Bcl-2, and inhibits the activation of caspase family proteins, reducing cell apoptosis
COLA FLAVOR Ingredients: purified water, L-Carnitine tartrate (Carnipure), acidulant: monohydrate citric acid, flavor: cola, potassium sorbate, sodium benzoate, sweetener: sucralose, pyridoxine hydrochloride (vitamin B6) and colorant: E-150d
A previous rodent experiment showed that NLRP3 inflammasome activation in retinal Mller cells drives IL-1 production, contributing to pericyte loss and microvascular dysfunction in diabetic mice (43)
