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They are a good deal bigger than a different class of compounds that we call small molecules
Dehydration can affect energy, digestion, exercise tolerance and hunger cues
MariTide, developed by Amgen, is a first-in-class antibody-peptide conjugate that combines GLP-1 receptor agonism with GIP receptor antagonism in a single molecule designed for once-monthly dosing
The primary endpoints were changes in body mass index (BMI), Hospital Anxiety and Depression Scale (HADS) scores, and Kansas City Cardiomyopathy Questionnaire Overall Summary Score (KCCQ-OSS) from baseline to one year
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