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Treatment with GLP-1RAs can regulate several pivotal miRNAs (such as miR-93-5p, miR-181a-5p and miR-34a-5p and miR-26a-5p) to inhibit apoptosis in endothelium [116]
Exendin 939 targets the extracellular side of the TRPV1 channel but does not share the CAP binding site Next, we examined the molecular target of exendin 939 on the TRPV1 channel via a patchclamp competition assay in CHO K1 cells expressing human TRPV1
161 Overactivation of ionotropic receptors as well as mechanoporation of cellular membranes 162 lead to a massive Ca 2+ entry that mediates cellular death
Gorio A, Di Giulio AM, Tenconi B, et al
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