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The company has operated since 2018, giving them more track record than newer entrants

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Cagrilintide dosing in combination trials starts at 0.3 mg once weekly and is titrated in stepwise increments up to 4.5 mg weekly based on tolerability and efficacy data from the CagriSema and related trials

However, a later analysis looking specifically at patients with early ALS those within one year from symptom onset revealed that those given methylcobalamin had a significantly slower progression compared with those on a placebo