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Carnitine also functions as an endogenous thyroid hormone nuclear uptake inhibitor that can impede the nuclear transfer of triiodothyronine (T3) and thyroxine (T4), thereby inhibiting the biological activity of thyroid hormones [78]

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Identifying and revealing the molecular mechanisms of how pathogens sense and uptake eukaryotic metabolites will increase our understanding of bacterial pathogenesis and potentially lead to new strategies to therapeutically target host metabolism as an antimicrobial strategy

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