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Key Takeaways: Retatrutide (Triple-G Peptide) is a next-generation, triple-hormone GLP-1/GIP/glucagon medication currently in clinical trials, showing record-breaking fat-loss potential
Kong, A
If intranasal delivery achieves preferential brain delivery at the expense of systemic exposure, the hepatic glucagon receptor activation would be reduced
This sustained satiety often reduces appetite and overall calorie intake, but can also contribute to side effects like nausea, vomiting, bloating, and constipation
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