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Intervention trials indicate that combined probiotic and prebiotic supplementation can significantly decrease TPOAb and TgAb concentrations, improve gut barrier integrity, and restore microbial diversity in HT patients (Liu et al

The FDA must still determine whether to accept the committees recommendations and complete the remaining regulatory process

The decision should be individualized based on the patient's surgical procedure type, time since surgery, current metabolic status, and treatment goals

Despite a relatively short half-life of approximately 30 minutes, the peptide triggers gene expression changes that persist and cascade independently of its continued presence