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8,9 Table 1 Risk Factors for Vitamin B12 Deficiency A multicenter randomized controlled trial of 390 patients with diabetes mellitus showed that those taking 850 mg of metformin three times per day had an increased risk of vitamin B 12 deficiency (number needed to harm = 14 per 4.3 years) and low vitamin B 12 levels (number needed to harm = 9 per 4.3 years) vs

The sample size dwarfed that of Littmans original study, which was based on 256 parental reports

( WADA allows athletes to use non-pharmaceutical interventions, such as hypobaric chambers, to raise EPO levels.) Anabolic steroids can cause mood swings, shrunken testicles, baldness, and infertility, and can suppress the bodys ability to produce testosterone on its own

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