Initial assessment showed that the FITC conjugate peptides recapitulated the pharmacological properties of their unmodified counterparts, with similar binding affinity but reduced cAMP signalling potency for lixisenatide-FITC compared to exendin-4-FITC (Figure 3E, 3F)
Complete Peptide Half-Life Chart The table below summarizes plasma half-life, lyophilized storage temperature, reconstituted stability at 28 C, and typical research dose ranges reported in the peer-reviewed literature and in pharmacokinetic modeling studies
More serious risks include: Low blood sugar (hypoglycemia): Especially when used with other medicines to treat diabetes, low blood sugar may occur, with symptoms such as dizziness, sweating, blurred vision, or confusion
Hepatology 31 , 391398, doi: 10.1002/hep.510310219 (2000)