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Glu excitotoxicity results in excessive influx of extracellular Ca 2+ through the overstimulation of NMDAR, which may cause the release of Ca 2+ from intracellular stores, further increasing the concentration of cytosolic free Ca 2+ [46]
They should be able to offer personalized guidance from there.
To balance risks and benefits, expert opinions emphasize the importance of individualized dosing, shared decision-making, and careful patient selection
GLP-1 receptor agonists enhance glucose-dependent insulin secretion from pancreatic beta cells, meaning they stimulate insulin release only when blood glucose levels are elevated
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