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The LIRA-RENAL Trial (Once-Daily Liraglutide) The Efficacy and Safety of Liraglutide Versus Placebo as Add-on to Glucose-Lowering Therapy in Patients With Type 2 Diabetes and Moderate Renal Impairment (LIRA-RENAL) trial investigated the efficacy and safety of liraglutide as an add-on to existing glucose-lowering medications in people with inadequately controlled T2DM and moderate renal impairment (stage 3 CKD, eGFR 3059 ml/min/1.73 m 2 ) [48]
Women should be aware of this potential effect and stay on top of it with their healthcare providers
higher doses do not guarantee bigger benefits and can increase side-effect risk
Certain medical conditions or medications could make it unsafe
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