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Insurance reviewers evaluate BMI (typically requiring 30 or 27 with comorbidities), previous weight loss intervention attempts, existing metabolic conditions, and provider rationale for GLP-1 selection
Single-nucleus RNA-seq libraries were generated using a Chromium Single Cell 3 Library and Gel Bead Kit v3 (10 Genomics, Pleasanton, CA) according to the manufacturers protocol
Additionally, the dual action helps preserve beta-cell function in the pancreas, potentially slowing disease progression in people with type 2 diabetes
This is especially true for compounds like GLP-1 and GIP that can greatly impact metabolic health
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