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In terms of weight loss, if you have a vitamin B12 deficiency, which is likely, you will lose some of the vitamin B12 shot in the first 48 hours, but at least 50% of it will be stored in your liver

Like many therapeutic peptides, it may require daily (or near-daily) administration, as in the previously referenced mouse and rabbit studies.12 17 Moreover, as a preventive or a drug for managing chronic health conditions, treatment ought to be ongoing and may involve periodic breaks in dosing (cycling), which is also common with many therapeutic peptides

As with any chronic-disease therapy, the decision should be individualized with a clinician who knows your full history

Taking measurements (waist, hips, arms, thighs), progress photos every few weeks, and noting how clothes fit gives you a more complete picture of progress than the scale alone