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The absence of the gallbladder does not fundamentally alter tirzepatide's pharmacokinetics, as the medication is administered subcutaneously and undergoes proteolytic degradation rather than requiring biliary processing for absorption or metabolism
Clinical trials show average weight loss ranging from approximately 1017% of total body weight over 1218 months when combined with lifestyle changes
Right now, the data they have on how the drug may impact oral contraceptives is slim, but is listed on the drugs label to be safe
When clinically appropriate, GLP-1 therapy can help lower cardiometabolic strain and inflammatory burden while complementing, not replacing, lifestyle fundamentals such as nutrient-dense eating, regular movement, resistance training, adequate protein intake, and restorative sleep
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