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While the list of pathophysiologic defects continues to grow, the ominous octet provides a representation of 8 key defects found in T2DM ( Figure 1 )
This is clinically significant because excess abdominal fat is directly linked to insulin resistance, chronic inflammation, and elevated cardiovascular risk
Indeed, as much as 50% of post-MI myocardial injury is attributable to IRI (3)
Semaglutide GLP-1 is administered as a once-weekly injection under the skin (subcutaneous injection) for weight loss
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