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As a GLP-1/GIP/glucagon receptor agonist, it may theoretically delay gastric emptying, which is a class-related effect that could affect the absorption of orally administered medicines

In IELs specifically, the activation of GLP-1R signaling suppresses phosphorylation of chainassociated protein kinase 70 (ZAP70) and its downstream target SH2 domaincontaining leukocyte protein 76 (SLP-76), leading to dampening of proximal T cell receptor signaling and reduced cytokine transcription

Inhibition of glutathione S-transferase 3-3 by glutathione derivatives that bind covalently to the active site