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That means the requesting team should document the experimental purpose, confirm that internal handling aligns with non-clinical use, and keep staff clear on the difference between investigational laboratory materials and approved medical products

Furthermore, given that we have demonstrated that this mitochondrial adaptation is to promote rebalancing of pyrimidine levels, mitochondrial biogenesis could also be used to identify patient cohorts likely to benefit from UCK2 inhibitor combinations

Similar results have been observed in studies involving the MCL and other connective tissues

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